abstract：BACKGROUND:Intermedin (IMD) is involved in the prevention of atherosclerotic plaque progression, possessing cardioprotective effects from hypertrophy, fibrosis and ischemia-reperfusion injury. Elevated plasma IMD levels have been demonstrated in patients with acute coronary syndromes. No human study has examined the ro...

journal_title：BMC cardiovascular disorders

authors： Yamac AH,Bacaksiz A,Ismailoglu Z,Kucukbuzcu S,Sevgili E,Asoglu E,Nasifov M,Jafarov P,Erdogan E,Goktekin O

更新日期：2014-12-11 00:00:00

abstract：BACKGROUND:Idiopathic ventricular tachycardia (VT) and/or premature ventricular contractions (PVCs) arise most commonly from the right ventricular outflow tract and less frequently from the left ventricular outflow tract (LVOT), either below or above the semilunar valves. CASE PRESENTATION:We report a case of 24-year-...

journal_title：BMC cardiovascular disorders

authors： Gouda S,Wichterle D,Peichl P,Kautzner J

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:Depression is common in patients with cardiometabolic diseases but little is known about the relationship, if any, between cardiovascular risk factor values and depressive symptoms in patients with these conditions. The objective of this paper is to study the association between cardiovascular risk factors a...

journal_title：BMC cardiovascular disorders

authors： Jani BD,Cavanagh J,Barry SJ,Der G,Sattar N,Mair FS

更新日期：2014-10-28 00:00:00

abstract：BACKGROUND:Here we investigated Brahma-related gene 1 (BRG1) expression in aortic smooth muscle cells (SMCs) and its role in the regulation of the pathological changes in aortic SMCs of thoracic arotic dissection (TAD). METHODS:BRG1, matrix metalloproteinase 2 (MMP2), and MMP9 mRNA and protein expression in human aort...

journal_title：BMC cardiovascular disorders

authors： Yuan Y,Wang C,Xu J,Tao J,Xu Z,Huang S

更新日期：2014-10-11 00:00:00

abstract：BACKGROUND:Sudden cardiac death (SCD) among the young is a rare and devastating event, but its exact incidence in many countries remains unknown. An autopsy is recommended in every case because some of the cardiac pathologies may have a genetic origin, which can have an impact on the living family members. The aims of ...

journal_title：BMC cardiovascular disorders

authors： Hofer F,Fellmann F,Schläpfer J,Michaud K

更新日期：2014-10-07 00:00:00

abstract：BACKGROUND:Whilst it is well known that psychosocial determinants may contribute to cardiovascular diseases (CVD), data from specific groups are scarce. The present study aims to determine the contribution of psychosocial determinants in increasing the risk of cardiovascular events (myocardial infarction and stroke), a...

journal_title：BMC cardiovascular disorders

authors： Mejía-Lancheros C,Estruch R,Martínez-González MA,Salas-Salvadó J,Castañer O,Corella D,Arós F,Gómez-Gracia E,Fiol M,Lapetra J,Serra-Majem L,Pintó X,Ros E,Díez-Espino J,Basora J,Sorlí JV,Lamuela-Raventos RM,Ruiz-Gutiérrez

更新日期：2014-10-03 00:00:00

abstract：BACKGROUND:Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that correlates with cardiac events. This study assessed the association between NLR and the presence of chronic coronary total occlusion (CTO). METHODS:The study population included 225 patients, a control group (n = 75), a coronary ...

journal_title：BMC cardiovascular disorders

authors： Demir K,Avci A,Altunkeser BB,Yilmaz A,Keles F,Ersecgin A

更新日期：2014-09-27 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is a life-threatening arrhythmia that carries the high risk of thromboembolic complication. Stroke often develops in patients who undergo successful Cox Maze procedure, despite the fact that the procedure has shown a high rate of success in sinus conversion from AF. This study examin...

journal_title：BMC cardiovascular disorders

authors： Kim JS,Lee SA,Park JB,Chee HK,Chung JW

更新日期：2014-09-11 00:00:00

abstract：BACKGROUND:Suspected nonischemic cardiomyopathy (NICM) is a common clinical setting with highly variable prognosis. Early noninvasive risk-stratification is important for justification of invasive examinations, specific treatment and patient surveillance. We studied the additional prognostic value of late gadolinium en...

journal_title：BMC cardiovascular disorders

authors： Pöyhönen P,Kivistö S,Holmström M,Hänninen H

更新日期：2014-08-27 00:00:00

abstract：BACKGROUND:The optimal cutoff of the waist-to-hip ratio (WHR) among Han adults in Xinjiang, which is located in the center of Asia, is unknown. We aimed to examine the relationship between different WHRs and cardiovascular risk factors among Han adults in Xinjiang, and determine the optimal cutoff of the WHR. METHODS:...

journal_title：BMC cardiovascular disorders

authors： Li SS,Pan S,Ma YT,Yang YN,Ma X,Li XM,Fu ZY,Xie X,Liu F,Chen Y,Chen BD,Yu ZX,He CH,Zheng YY,Abudukeremu N,Abuzhalihan J,Wang YT

更新日期：2014-07-29 00:00:00

abstract：BACKGROUND:Cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) imaging is increasingly used to assess myocardial involvement in patients with Fabry disease, an X linked lipid storage disorder. However, it is often proposed as an optional tool. A different cardiomyopathic disease progression b...

journal_title：BMC cardiovascular disorders

authors： Sechi A,Nucifora G,Piccoli G,Dardis A,Bembi B

更新日期：2014-07-16 00:00:00

abstract：BACKGROUND:Electronic cigarettes have been developed and marketed in recent years as smoking substitutes. However, no studies have evaluated their effects on the cardiovascular system. The purpose of this study was to examine the immediate effects of electronic cigarette use on left ventricular (LV) function, compared ...

journal_title：BMC cardiovascular disorders

authors： Farsalinos KE,Tsiapras D,Kyrzopoulos S,Savvopoulou M,Voudris V

更新日期：2014-06-23 00:00:00

abstract：BACKGROUND:It is uncertain whether gender differences in outcome after primary percutaneous coronary intervention (PCI) are only attributable to different baseline characteristics or additional factors. METHODS:Databases of two German myocardial infarction network registries were combined with a total of 1104 consecut...

journal_title：BMC cardiovascular disorders

authors： Birkemeyer R,Schneider H,Rillig A,Ebeling J,Akin I,Kische S,Paranskaya L,Jung W,Ince H,Nienaber CA

更新日期：2014-06-02 00:00:00

abstract：BACKGROUND:To estimate the short- and long-term financial impact of early referral for implantable loop recorder diagnostic (ILR) versus conventional diagnostic pathway (CDP) in the management of unexplained syncope (US) in the Portuguese National Health Service (PNHS). METHODS:A Markov model was developed to estimate...

journal_title：BMC cardiovascular disorders

authors： Providência R,Candeias R,Morais C,Reis H,Elvas L,Sanfins V,Farinha S,Eggington S,Tsintzos S

更新日期：2014-05-06 00:00:00

abstract：BACKGROUND:Iron may damage sarcomeric proteins through oxidative stress. We explored the left ventricular (LV) torsional mechanics in patients with beta-thalassaemia major and its relationship to myocardial iron load. Using HL-1 cell and B6D2F1 mouse models, we further determined the impact of iron load on proteolysis ...

journal_title：BMC cardiovascular disorders

authors： Chen MP,Li SN,Lam WW,Ho YC,Ha SY,Chan GC,Cheung YF

更新日期：2014-04-12 00:00:00

abstract：BACKGROUND:The incidence of clinically apparent stroke in transcatheter aortic valve implantation (TAVI) exceeds that of any other procedure performed by interventional cardiologists and, in the index admission, occurs more than twice as frequently with TAVI than with surgical aortic valve replacement (SAVR). However, ...

journal_title：BMC cardiovascular disorders

authors： Fanning JP,Wesley AJ,Platts DG,Walters DL,Eeles EM,Seco M,Tronstad O,Strugnell W,Barnett AG,Clarke AJ,Bellapart J,Vallely MP,Tesar PJ,Fraser JF

更新日期：2014-04-05 00:00:00

abstract：BACKGROUND:Optimal treatment of acute ST-elevation myocardial infarction (STEMI) involves rapid diagnosis, and transfer to a cardiac centre capable of percutaneous coronary intervention (PCI) for immediate mechanical revascularisation. Successful treatment requires rapid return of perfusion to the myocardium achieved b...

journal_title：BMC cardiovascular disorders

authors： Johnson TW,Marsden D,Mumford A,Pike K,Mundell S,Butler M,Strange JW,Bowles R,Rogers C,Baumbach A,Reeves BC

更新日期：2014-04-04 00:00:00

abstract：BACKGROUND:Studies adopting electronic medical records and genomic information are becoming widespread. Through this new modality in research, it is possible to study how genetic variants influence susceptibility towards chronic conditions and can improve patient care.Our aim is to develop a biobank with 2,000 heart fa...

journal_title：BMC cardiovascular disorders

authors： Gioli-Pereira L,Bernardez-Pereira S,Goulart Marcondes-Braga F,Rocha Spina JM,Muniz Miranda da Silva R,Evangelista Ferreira N,Bacal F,Fernandes F,Mansur AJ,Krieger JE,Costa Pereira A

更新日期：2014-03-04 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) is one of the most common diseases leading to mortality and morbidity worldwide. There is considerable debate on whether serum transforming growth factor β1 (TGF-β1) levels are associated with long-term major adverse cardiovascular events in patients with CAD, and to date, no st...

journal_title：BMC cardiovascular disorders

authors： Chen C,Lei W,Chen W,Zhong J,Gao X,Li B,Wang H,Huang C

更新日期：2014-02-17 00:00:00

abstract：BACKGROUND:Mitral stenosis, one of the grave consequences of rheumatic heart disease, was generally considered to take decades to evolve. However, several studies from the developing countries have shown that mitral stenosis follows a different course from that seen in the developed countries. This study reports the pr...

journal_title：BMC cardiovascular disorders

authors： Tadele H,Mekonnen W,Tefera E

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The aim of the study was to investigate the relationship between the ejection fraction (EF) and the mitral annular systolic velocity (Sm) in patients with preserved left ventricular systolic function (EF>55%). The study task was to evaluate whether the assessment of Sm(avg) can be used as an alternative to t...

journal_title：BMC cardiovascular disorders

authors： Daskalov IR,Daskalova IK,Demirevska LD,Atzev BG

更新日期：2013-10-26 00:00:00

abstract：BACKGROUND:Cardiovascular diseases (CVDs) are one of the leading causes of death and disability in the world. Over 80% of CVD deaths take place in low-and middle-income countries. One-third of the population aged above 40 years suffers from Hypertension (HTN) and this is largely unreported as there is no registry for C...

journal_title：BMC cardiovascular disorders

authors： Khan MA,Javed W,Ahmed M,Walley J,Khan HJ

更新日期：2013-09-25 00:00:00

abstract：BACKGROUND:In adults, impaired myocardial repolarization and increased risk of arrhythmia are known consequences of open heart surgery. Little is known, however, about post-operative consequences of cardiopulmonary bypass surgery in children. The aim of this study was to assess ventricular repolarization and coronary p...

journal_title：BMC cardiovascular disorders

authors： Aburawi EH,Souid AK,Liuba P,Zoubeidi T,Pesonen E

更新日期：2013-09-10 00:00:00

abstract：BACKGROUND:CYP2C19*2 polymorphism is related to metabolizer phenotypes resulting in reduced effectiveness in converting the antiplatelet drug clopidogrel to active drug. An association of the genotype itself with adverse outcomes is discussed. We investigated the prognostic value of carriage of the CYP2C19*2 allele in ...

journal_title：BMC cardiovascular disorders

authors： Rothenbacher D,Hoffmann MM,Breitling LP,Rajman I,Koenig W,Brenner H

更新日期：2013-08-27 00:00:00

abstract：BACKGROUND:The known risk factors for coronary heart disease among people prior suffering an out-of-hospital cardiac arrest with validated myocardial infarction aetiology and their thoughts about what lifestyle means to them after surviving have rarely been described. Therefore the aim of the study was to describe risk...

journal_title：BMC cardiovascular disorders

authors： Forslund AS,Lundblad D,Jansson JH,Zingmark K,Söderberg S

更新日期：2013-08-27 00:00:00

abstract：BACKGROUND:Chronic heart failure requires a complex treatment regimen on a life-long basis. Therefore, self-care/self-management is an essential part of successful treatment and comprehensive patient education is warranted. However, specific information on program features and educational strategies enhancing treatment...

journal_title：BMC cardiovascular disorders

authors： Meng K,Musekamp G,Seekatz B,Glatz J,Karger G,Kiwus U,Knoglinger E,Schubmann R,Westphal R,Faller H

更新日期：2013-08-23 00:00:00

abstract：BACKGROUND:Ectonucleotidase plays an important role in the regulation of cardiac function by controlling extracellular levels of adenine nucleotides and adenosine. To determine the influence of ischemia-reperfusion injury on ectonucleotidase activity in coronary vascular bed, we compared the metabolic profile of adenin...

journal_title：BMC cardiovascular disorders

authors： Takahashi-Sato K,Murakawa M,Kimura J,Ito MA,Matsuoka I

更新日期：2013-07-28 00:00:00

abstract：BACKGROUND:Increasing rates of percutaneous coronary intervention (PCI) and decreasing rates of coronary artery bypass graft (CABG) surgery followed the introduction of drug eluting stents in Western Australia in 2002. We assessed the impact of these changes on one-year outcomes for the total population of patients und...

journal_title：BMC cardiovascular disorders

authors： Sanfilippo FM,Rankin JM,Hobbs MS,Nguyen M,Knuiman MW,Berg P,Whitford EG,Hendriks R,Hockings BE,Muhlmann M,Newman M,Larbalestier R,Gilfillan I,Briffa TG

更新日期：2013-07-05 00:00:00

abstract：BACKGROUND:Mean platelet volume has been associated with stroke in patients with atrial fibrillation. However, its role as a predictor of left atrial stasis, assessed by transesophageal echocardiography, in patients with non-valvular atrial fibrillation has not yet been clarified. METHODS:Single center cross-sectional...

journal_title：BMC cardiovascular disorders

authors： Providência R,Faustino A,Paiva L,Fernandes A,Barra S,Pimenta J,Trigo J,Botelho A,Leitão-Marques AM

更新日期：2013-06-10 00:00:00

abstract：BACKGROUND:Early detection of heart failure is essential to effectively reduce related mortality. The quantification of the mechanical properties of the myocardium, a primordial indicator of the viability of the cardiac tissue, is a key element in patient's care. Despite an incremental utilization of multi-parametric m...

journal_title：BMC cardiovascular disorders

authors： Périé D,Dahdah N,Foudis A,Curnier D

更新日期：2013-03-27 00:00:00

abstract：BACKGROUND:Atherosclerosis (AT) is a chronic inflammatory disease characterized by the accumulation of inflammatory cells, lipoproteins and fibrous tissue in the walls of arteries. AT is the primary cause of heart attacks and stroke and is the leading cause of death in Western countries. To date, the pathogenesis of AT...

journal_title：BMC cardiovascular disorders

authors： Karagiannis GS,Weile J,Bader GD,Minta J

更新日期：2013-01-16 00:00:00

abstract：BACKGROUND:Hypertension is a growing public health problem in many developing countries including Ethiopia. However, its prevention and control has not yet received due attention. This study aimed to determine the prevalence and associated factors of hypertension among adults in Gondar city, North-West Ethiopia. METHO...

journal_title：BMC cardiovascular disorders

authors： Awoke A,Awoke T,Alemu S,Megabiaw B

更新日期：2012-11-28 00:00:00

abstract：BACKGROUND:We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD). METHODS:A retrospective analysis was performed including 200 patients registered in the Regione Campania network (aged 62.4 ± 12, male 64%). HRV analysis was ...

journal_title：BMC cardiovascular disorders

authors： Melillo P,Izzo R,De Luca N,Pecchia L

更新日期：2012-11-15 00:00:00

abstract：BACKGROUND:Areca nut (commonly known as betel nut) chewing has been shown to be associated with metabolic syndrome and cardiovascular disease (CVD). The mechanism by which betel nut ingestion could lead to development of CVD is not precisely known; however, dyslipidemia, hyperhomocysteinemia, hypertriglyceridemia and i...

journal_title：BMC cardiovascular disorders

authors： Iqbal MP,Mehboobali N,Haider G,Pervez S,Azam I

更新日期：2012-10-24 00:00:00

abstract：BACKGROUND:There is limited information about any association between the onset of atrial fibrillation (AF) and the presence of valvular disease. METHODS:We retrospectively examined 940 patients in sinus rhythm, examined by echocardiography in 1996. During 11 years of follow-up, we assessed the incidence of AF and out...

journal_title：BMC cardiovascular disorders

authors： Widgren V,Dencker M,Juhlin T,Platonov P,Willenheimer R

更新日期：2012-10-18 00:00:00

abstract：BACKGROUND:Neointimal formation in atherosclerosis has been subject for intense research. However, good animal models mimicking asymmetrical lesion formation in human subjects have been difficult to establish. The aim of this study was to develop a model which would lead to the formation of eccentric lesions under macr...

journal_title：BMC cardiovascular disorders

authors： Kivelä A,Hartikainen J,Ylä-Herttuala S

更新日期：2012-10-17 00:00:00

abstract：BACKGROUND:Genetic variation at 1p13 modulates serum lipid levels and the risk of coronary heart disease through the regulation of serum lipid levels. Here we investigate if the interaction between genetic variants at 1p13 and serum lipid levels affects the risk of non-fatal myocardial infarction (MI) in the Stockholm ...

journal_title：BMC cardiovascular disorders

authors： Gigante B,Leander K,Vikström M,Ye S,de Faire U

更新日期：2012-10-16 00:00:00

abstract：BACKGROUND:Anomalous aortic origin of the coronary artery (AAOCA) from the opposite sinus of Valsalva with an interarterial course has received much attention due to its association with sudden death in otherwise healthy individuals. AAOCA is relatively common and may have significant public health implications. While ...

journal_title：BMC cardiovascular disorders

authors： Peñalver JM,Mosca RS,Weitz D,Phoon CK

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Care pathways have become a popular tool to enhance the quality of care by improving patient outcomes, promoting patient safety, increasing patient satisfaction, and optimizing the use of resources. We performed a disease specific systematic review to determine how care pathways in the hospital treatment of ...

journal_title：BMC cardiovascular disorders

authors： Kul S,Barbieri A,Milan E,Montag I,Vanhaecht K,Panella M

更新日期：2012-09-25 00:00:00

abstract：BACKGROUND:Lipid accumulation product (LAP) has been advocated as a simple clinical indicator of metabolic syndrome (MS). However, no studies have evaluated the accuracy of LAP in predicting MS in Taiwanese adults. The aim of our investigation was to use LAP to predict MS in Taiwanese adults. METHODS:Taiwanese adults ...

journal_title：BMC cardiovascular disorders

authors： Chiang JK,Koo M

更新日期：2012-09-24 00:00:00